Amodis 400mg Tablet

✔️ Uses of Amodis 400

• Treatment of Bacterial Infections
• Treatment of Parasitic Infections

✔️ Side Effects of Amodis 400

• Metallic smell
• Nausea
• Vomiting
• Diarrhea,
• Drowsiness, and
• Rash may occur during treatment.

✔️ How to use Amodis 400

• Follow your doctor's instructions regarding the dosage and duration of Amodis 400 Tablet.
• Swallow the tablet whole, without crushing, chewing, or breaking it.
• Take Amodis 400 Tablet with food.

✔️ Quick Suggestions:

• Follow your doctor's instructions carefully regarding the dosage, duration, and frequency of taking Amodis 400. Do not change the dosage or stop taking it without consulting your doctor.
• Take Amodis 400 with food to reduce the risk of stomach upset. Swallow the tablet whole with a full glass of water, and do not crush, break, or chew the tablet.
• It is important to complete the full course of Amodis 400 as prescribed by your doctor, even if you feel better before the end of the treatment period. Stopping the medication early may cause the infection to return or worsen.
• Avoid consuming alcohol while taking Amodis 400, as this can cause severe nausea, vomiting, and other unpleasant side effects.
• Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking Metronidazole 400mg, as it may not be safe for use during pregnancy or breastfeeding.

✔️ Indications of Amodis 400

Amodis 400 is an antibiotic that aids your body's defenses against bacterial and parasitic infections. Metronidazole is used to treat the following conditions:

• The prevention of anaerobic bacteria-related post-operative infections (particularly species of Bacteroides and anaerobic streptococci).
• Anaerobe-caused septicemia, bacteremia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis, and post-operative wound infections.
• When treating urogenital trichomoniasis.
• Vaginosis is caused by bacteria (also known as non-specific vaginitis).
• Amoebiasis in all its forms (intestinal, extra-intestinal disease, and symptomless cyst passers).
• Giardiasis.
• Gingivitis with acute ulceration.
• Leg ulcers and pressure sores are caused by anaerobic bacteria.
• Anaerobic organisms cause acute dental infections.
• Pseudomembranous colitis caused by antibiotics

✔️ Pharmacology of Amodis 400

Metronidazole is an antiprotozoal medication that belongs to the imidazole class of antibacterial drugs. Metronidazole's 5 nitro group is reduced by anaerobic bacteria metabolism. According to research, the reduced form of this drug interacts with DNA and produces metronidazole's bactericidal effect.

✔️ Dosage & Administration of Amodis 400

Tablet and Suspension:

Trichomoniasis (Adults & Children over 10 yrs) (Adults & Children over 10 yrs) - 

• 400 mg bid for 7 days, or 200 mg tid.
• For two days, take 800 mg in the morning and 1-2 gm at night.
• 1 day of a single dose of 2 grams

Trichomoniasis (Children)-

• Children 7 to 10 years old: 100 mg twice daily
• Kids aged 3 to 7: 100 mg twice daily
• 50 mg twice daily for kids aged 1-3.

Amoebic enteritis (Adults & Children over 10 yrs)-

• 800 mg five days per day

Amoebic enteritis (Children)-

• Children 7 to 10 years old: 400 mg twice daily
• 200 mg qid for children ages 3 to 7
• 200 mg twice daily for kids aged 1-3.

Asymptomatic extra-intestinal amoebiasis (Adults & Children over 10 yrs)-

• 400–800 mg once daily for 5–10 days.

Children with extra-intestinal and asymptomatic amoebiasis:

• Kids aged 7 to 10: 200–400 mg twice daily
• 100–200 mg qid for children aged 3–7 years.
• 100-200 mg tid for children ages 1-3

Adults and children over the age of 10 who have giardiasis

• once everyday for three days, 2 gram

Children's Giardiasis:

• Children aged 7 to 10: 1 gram once a day
• Children ages 3 to 7: 600 to 800 mg once daily
• 1-3 years old children: 500 mg once daily

Adults and children older than 10 years who have acute ulcerative Gingivitis:

• tid for 3 days at 200 mg

Children's acute ulcerative gingivitis

• 7 to 10 year old children: 100 mg twice day
• 100 mg twice day for children ages 3 to 7,
• 50 mg twice daily for children ages 1-3.

Acute dental infections in adults and kids older than 10 years:

• tid for 3–7 days at 200 mg

Adults and children over the age of 10 who have bacterial vaginosis:

• A single dose of 2 gm for 1 day followed by 400 mg once a day for 7 days.

Pressure sores and leg ulcers (Adults and Children Over 10 Years)

• tid for seven days at 400 mg

Anaerobic infections in adults and kids older than 10 years:

• 800 mg at first, then 400 mg every day for seven days.
• Children's anaerobic infections
• 7.5 mg/kg tid for children aged 1 to 10

Surgery prevention (adults and children older than 10 years):

• 400 mg tid for one day beginning 24 hours before surgery

Surgery prevention (for children):

• 7.5 mg/kg tid for children aged 1 to 10

✔️ Interaction

• Amodis 400mg Tablet used to treat HIV (amprenavir), anticoagulants (anisindione, dicumarol, warfarin), some immunizations (BCG, cholera vaccine live, typhoid vaccine live), anti-cancer drugs (busulfan), and drugs containing ethanol may interact with Amodis 400mg Tablet.
• To prevent unpleasant side effects like sickness, vomiting, stomach pain, palpitations, headaches, and heat flushes, it is advised that you abstain from drinking while receiving therapy with Amodis 400mg Tablet and for 48 hours after finishing the term.
• Tell your doctor if you have peripheral neuropathy, heart, kidney, or liver issues as well as diarrhea linked with Clostridium difficile, bone marrow depression or low blood count, CNS disease, epilepsy, or porphyria (a blood disorder).

✔️ Contraindications

Patients who have a history of allergy to metronidazole or other nitroimidazole derivatives should not use metronidazole.

✔️ Pregnancy & Lactation

The US FDA classifies pregnancy with metronidazole as B. However, there are no adequate and well-controlled studies on pregnant women. Because animal reproduction studies do not always predict human response, the drug should be used during pregnancy only when clearly necessary. Metronidazole has been shown to be excreted in human milk. Therefore, caution should be exercised when administering metronidazole to lactating women.

✔️ Precautions & Warnings

It is advised to perform hematological tests, particularly white blood cell counts, and monitor the patient for adverse reactions like peripheral or central neuropathy (such as feeling abnormal., Ataxia, dizziness, and seizures) if metronidazole must be administered for a longer period of time than is typically recommended.
Patients with hepatic encephalopathy should use metronidazole cautiously.
Patients should be made aware that metronidazole can cause their urine to turn black.

✔️ Storage Conditions

Store below 30°C. Keep protected from light. Keep medicines out of the reach of children. Do not use it later than the date of expiry.